![]() PaCO₂ was higher than PACO₂ in the controls (5.2☐.5 vs. ![]() In ARDS patients, PeCO₂ was higher with DB (2.1☐.4 kPa) compared to VC (1.8☐.4 kPa, p<0.05). PeCO₂ determined with MM (3.2☐.4 kPa) was higher compared to DB (2.5☐.3 kPa, p<0.05) and VC (2.5☐.3 kPa, p<0.05) in the controls. Results: In ARDS patients, dead space determined with VC (53☘%) was lower compared to DB (68☘%, p<0.0001) and MM (72☘%, p<0.0001). PeCO₂ was measured in expired air using a Douglas bag (DB) and via indirect calorimetry with a metabolic monitor (MM). Dead space was also calculated using the Bohr-Enghoff modification (arterial CO₂ tension (PaCO₂) instead of PACO₂). ![]() Both variables were calculated from a mathematical fit of the volumetric capnogram. Methods: In 15 ARDS patients and 15 controls (post-operative cardiac surgery) dead space (V D) was calculated with VC using the Bohr equation: V D/V T = (PACO₂-PeCO₂)/PACO₂, where PACO₂ and PeCO₂ are alveolar and mixed expired CO₂ tension. Our aim was to compare VC with current techniques in ARDS patients and controls. ![]() Recently, a novel technique based on volumetric capnography (VC) was validated. However, dead space calculation is cumbersome using current techniques. This parameter is important in patients with acute respiratory distress syndrome (ARDS) for treatment follow-up, ventilator settings optimization and prognostication. Session: Lung function testing: new findings and new approaches Session type: Thematic Poster SessionĪbstract Introduction: Bohr's dead space is the portion of tidal volume (V T) not participating in gas exchange with pulmonary blood flow. ![]()
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